Despite being fiercely proud of their individuality, Spain’s regions share a common rhythm. From the lull of afternoon siestas to the riotous tapas bars and discotecas, Spain’s invigorating lifestyle will galvanize any traveler. For daring backpackers looking to elevate their adventures, Barcelona’s Parc de Collserola and Sevilla’s Parque Doñana provide diverse flora and fauna, breathtaking views, and challenging hikes. If the flatlands are more your cup of tea, check out the beaches of Ibiza off the coast of Catalonia, or explore the world-class art museums of Madrid. In this chapter, we have focused on a few major cities (Madrid, Barcelona, Sevilla, and Granada), the Mediterranean islands of Mallorca and Ibiza, and the northern party capital of Pamplona. We also cover the historic pilgrimage route to Santiago de la Compostela, which includes the smaller cities Burgos, Carrión de los Condes, León, and Astorga.